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Resource for Early-onset Alzheimer Disease Research — $25 Gift Card

READR is a study to understand the genetic factors influencing early-onset Alzheimer…

Resource for Early-onset Alzheimer Disease Research
To date, researchers have identified several genes that increase the risk for early-onset AD (i.e., the genes PSEN1, PSEN2, and APP). Yet, these genes only explain approximately 10% of early-onset AD, meaning much of early-onset AD is unexplained.

Our study has three goals. First, we are attempting to identify more genetic factors influencing early-onset AD. Second, we want to understand how these genes influence the progression of AD. And, third, we want to understand the relationship between early and late-onset forms of AD. To do this, we need the help of families like yours. We wish to enroll families with early-onset AD, complete cognitive assessments of the families, assess genetic factors in these families, and analyze the patterns of inheritance.

We determine eligibility based on the cognitive status and age of participants and their family members. Participation includes family and medical history questionnaires, assessments of memory and cognitive performance, and a blood draw. With appropriate permission, we will request to speak to family members or their representatives (usually spouses) to better understand memory and dementia history. We usually seek to enroll anyone in the family with AD, dementia, or memory problems, regardless of age, as well as those without dementia if age is over 50. Most activities occur by either phone or video conferencing (i.e., Zoom). To perform the genetic tests a blood sample will be collected in-person by a phlebotomist.

We may request repeat contacts/interviews over time. This is to update you and your family on the progress of the study, and to obtain current information on any cognitive changes among you or your family.


All participants are compensated upon completion of cognitive assessments and the collection of a blood sample.

Register Now!

To register for this study, you will need take a brief eligibility questionnaire and to provide your contact information. If you are registering on behalf of someone else, you will still be listed as the primary contact.

Reason for Interest

Briefly describe the reason the participant is interested in this study and why the participant should be considered eligible for participation.

Eligibility Questionnaire

Your answers to the questions below will be provided to the researcher to help determine eligibility for this study.

1. Do you or a family member have memory problems?


2. What was your or your family member's initial symptom(s)?


3. Did you or a living family member have memory problems before the age of 70?


4. Have you or your family member ever received any of the following diagnoses?


Contact Information

Demographic Information

Your gender and birthday are used to help determine eligibility for this study. The researcher will be provided with your gender and age (in years).

Your password must contain:
6 or more characters
Upper and lowercase letters
At least one number