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Transdiagnostic Brain-Behavior Profiling to Enhance Cognitive Behavioral Therapy Response — $600

This research is being done to better understand how Cognitive Behavioral Therapy…

Transdiagnostic Brain-Behavior Profiling to Enhance Cognitive Behavioral Therapy Response
Dr. Heide Klumpp (Ph.D.) at The University of Illinois at Chicago is conducting a research study on depression and anxiety in social situations. In this study, we are testing to see what behavior and brain function can tell us about treatment success in depression and/or anxiety using a standard psychotherapy (talk therapy) treatment for depression an anxiety disorders.

You may be eligible to participate if you:
1. Are 18-65 years old.
2. Suffer from depression and/or an anxiety disorder.

If you are eligible and agree to participate you will undergo:
1. A psychiatric interview.
2. Three functional MRI scans to non-invasively measure brain function.
3. Three sessions with electroencephalography (EEG) to non-invasively measure brain function.
4. Twelve weeks of standard treatment with talk therapy called Cognitive Behavioral Therapy (CBT)
5. OR twelve weeks of Supportive Therapy.

Interested volunteers should have no metal parts in their body and no major medical or neurological illness. Patients who are currently undergoing psychotherapy (talk therapy) or taking certain medications that affect the brain may not qualify for the study. Women should not be pregnant or trying to become pregnant.

The total time that you will be involved in this study is 22 visits. 21 of the 22 visits will occur during a 15-week period. You will also be asked to complete questionnaires at a 6-month follow up visit. You are expected to be in the study for about 38 hours. Volunteers will be compensated for their time. All information you give is confidential.


If you complete the study, you can receive a total of $600 (this includes compensation for the completion of behavioral tasks, compensation for completion of all optional tasks, and for completing the 6 month follow-up visit). You will receive your payment within approximately 8-12 weeks after the visit. It can be made on a per-visit basis or as a lump sum payment at completion/withdrawal from the study based on your preference by mail if you are not affiliated with UIC or direct deposit if you are affiliated with UIC. We may need to collect your social security number or Taxpayer Identification Number (TIN) in order to issue your compensation and for tax reporting purposes to the United States Internal Revenue Service (IRS).

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